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CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardio-Oncology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1558848
Myocardial Infarction and Pulmonary Embolism in Pancreatic Cancer: A Case Report of Two Manifestations of Trousseau's Syndrome
Provisionally accepted
Seok Oh 1
Ju Han Kim 1,2* Doo Sun Sim 1,2 Young Joon Hong 1,2
Youngkeun Ahn 1,2 Myung Ho Jeong 1,2,3- 1 Chonnam National University Hospital, Gwangju, Republic of Korea
- 2 Chonnam National University Medical School, Gwangju, Gwangju, Republic of Korea
- 3 Gwangju Veterans Hospital, Gwangju, Republic of Korea
The simultaneous occurrence of acute myocardial infarction (AMI) and venous thromboembolism (VTE) is rare and often associated with underlying malignancies. This study reports a rare case of concurrent AMI and pulmonary thromboembolism in a patient diagnosed with pancreatic cancer. Case presentation: A 70-year-old woman presented with acute chest pain and ST-segment elevation myocardial infarction, prompting immediate percutaneous coronary intervention (PCI) with the deployment of a drug-eluting stent. Following PCI, she was treated with optimal medical therapy, including dual antiplatelet therapy. Subsequent investigations revealed pulmonary embolism, deep vein thrombosis, and imaging findings suggestive of pancreatic cancer. Anticoagulation therapy was initiated to manage the VTE.Approximately 1 month after PCI, antithrombotic agents were temporarily discontinued for pancreatic mass biopsy, confirming pancreatic ductal adenocarcinoma. The patient was referred for palliative chemotherapy. Discussion: This case highlights the clinical manifestation of Trousseau's syndrome, characterized by cancer-associated thromboembolism, and underscores the importance of coordinated antithrombotic management in complex clinical settings.
Keywords: Cancer, Hypercoagulability, Myocardial Infarction, Pancreatic neoplasm, Pulmonary Embolism, Thrombosis, Venous Thromboembolism
Received: 11 Jan 2025; Accepted: 11 Mar 2025.
Copyright: © 2025 Oh, Kim, Sim, Hong, Ahn and Jeong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ju Han Kim, Chonnam National University Hospital, Gwangju, Republic of Korea
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