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ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Pediatric Cardiology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1558034
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The manuscript investigates the functional and morphological alterations in the fetal heart in hypertensive disorders of pregnancy (HDPs), a condition that significantly impacts cardiovascular health. The study highlights the sensitivity of the fetal right ventricle to hemodynamic changes, a key aspect in understanding heart function in both fetal and adult cardiovascular diseases. The exploration of uterine artery blood flow and its impact on fetal heart function, specifically through the assessment of right ventricular parameters, provides valuable insights into the role of mitochondrial function and its association with cardiovascular abnormalities.This work contributes to the growing body of evidence on the pathophysiology of heart-related diseases, particularly in the context of HDPs, and is highly relevant to the ongoing research on mitochondria-associated endoplasmic reticulum membranes (MAMs) in cardiovascular pathologies.
Keywords: LW and XF: Conceptualization, Data curation, Formal analysis, investigation, methodology, project administration, resources, Software
Received: 13 Jan 2025; Accepted: 09 Apr 2025.
Copyright: © 2025 Wang, Fu, Ren, Guo, Zhou, Yue and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Pengjie Zhang, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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