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CASE REPORT article
Front. Cardiovasc. Med.
Sec. Atherosclerosis and Vascular Medicine
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1551262
This article is part of the Research TopicAdvances in Spinal Cord Injury Prevention During Endovascular and Open Aortic RepairsView all articles
Aortic angiosarcoma leading to paraplegia: a case report
Provisionally accepted
Jing Li
Jiubo Sun*- Zibo Central Hospital, Shandong, China
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Background: Aortic angiosarcoma is a rare disease with atypical clinical symptoms. It often initially presents with embolic phenomena, such as lower limb arterial embolism, visceral embolism, or cerebral embolism, or as renovascular hypertension.Methods: There are no reported cases in the literature of spinal cord embolism caused by this condition. We report a case of a 76-year-old female patient whose abdominal CT showed a soft tissue mass in the left hip, involving the sacrum and iliac bone. Results: Aortic CTA revealed irregular filling defects in the aortic arch and descending aorta, highly suggestive of a tumor. A biopsy of the left hip mass confirmed the diagnosis of angiosarcoma. Immunohistochemistry results were positive for Vimentin, CD31, and ERG. Based on the patient's CTA findings, a diagnosis of aortic angiosarcoma with left hip soft tissue metastasis was made. The patient developed paraplegia and lower limb arterial embolism and died shortly afterward. This article briefly reviews the literature on aortic angiosarcoma.The purpose of this case report is to highlight the importance of monitoring common embolic sites in clinical practice, while also considering the possibility of rare sites, such as spinal cord embolism.
Keywords: Angiosarcoma, Aorta, case report, Paraplegia, spinal artery
Received: 25 Dec 2024; Accepted: 08 Apr 2025.
Copyright: © 2025 Li and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jiubo Sun, Zibo Central Hospital, Shandong, 255000, China
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