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SYSTEMATIC REVIEW article
Front. Cardiovasc. Med.
Sec. Atherosclerosis and Vascular Medicine
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1526326
This article is part of the Research Topic Cardiovascular Responses to Exercise: Clinical and Pathological Perspectives in Athletes View all articles
Effects of exercise training on left ventricular systolic and diastolic function after myocardial infarction: systematic review and meta-analysis
Provisionally accepted- 1 LANZHOU, China Lanzhou, China
- 2 The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, China
- 3 Lanzhou University, Lanzhou, Gansu Province, China
- 4 Gansu Provincial Maternal and Child Health Hospital, Lanzhou, Gansu Province, China
- 5 Gansu Provincial Hospital, Lanzhou, Gansu Province, China
Exercise training is a rehabilitative approach to improve cardiac function in patients with myocardial infarction. However, evidence on the effectiveness of exercise training in these patients remains limited. In this meta-analysis, we aim to evaluate the extent to which exercise training improves cardiac function in patients with myocardial infarctionWe conducted a systematic search of the PubMed, Embase, Cochrane Library, and Web of Science databases to compare cardiac function in myocardial infarction patients who received exercise training combined with standard pharmacological therapy. The cardiac function indicators evaluated included: LVEF, E, E/A, LVIDd, LVIDs, NT-proBNP, E' septal, GLS, and LVMI.The final analysis included 12 studies with a total of 922 patients. Compared with the standard treatment group, exercise training significantly improved LVEF (MD = 3.99, 95% CI: 1.30-6.68) and E (MD = 3.86, 95% CI: 1.33-6.39) in myocardial infarction patients, while showing no significant improvement in the remaining indicators
Keywords: exercise training, Left ventricular, Myocardial Infarction, Meta-analysis, LVEF (left ventricular ejection fraction)
Received: 11 Nov 2024; Accepted: 04 Mar 2025.
Copyright: © 2025 zhang, mi, Ding and gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
xin gao, Gansu Provincial Hospital, Lanzhou, 730000, Gansu Province, China
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