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CASE REPORT article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1486771
This article is part of the Research Topic Case Reports in Heart Surgery: 2024 View all 9 articles

Staged Surgical Management in ESRD: Case Report: Off-Pump CABG Followed by Renal Transplantation to Enhance Graft Survival

Provisionally accepted
Özge Çetinarslan Özge Çetinarslan *Davit SABA Davit SABA
  • Istanbul Florence Nightingale Hospital, Istanbul, Türkiye

The final, formatted version of the article will be published soon.

    Patients with end-stage renal disease (ESRD) have a significantly higher risk of cardiovascular diseases. In patients who are candidates for renal transplantation (RT), a major surgery such as coronary artery bypass grafting (CABG) is associated with cardiac complications as well as higher rates of post-operative complications, including the need for large amounts of blood transfusion, worsening of kidney function, infection, and graft rejection. Studies have shown that blood transfusions can increase the risk of graft rejection due to immune system activation. Off-pump CABG (OPCAB), also known as beating heart surgery, is a technique in which a heart-lung machine is not used, and the heart is not stopped. The main advantage of OPCAB surgery compared to on-pump CABG (ONCAB) is that it requires less blood product transfusion and has fewer renal, pulmonary, and hematological complications. This case series uniquely discusses two patients who underwent successful beating heart CABG without blood transfusion, followed by RT.

    Keywords: ESRD(end stage renal disease), OPCAB(off-pump coronary artery bypass grafting), ONCAB(on-pump coronary artery bypass grafting), renal transplantation (RT), staged surgery vs combined surgery

    Received: 26 Aug 2024; Accepted: 20 Jan 2025.

    Copyright: © 2025 Çetinarslan and SABA. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Özge Çetinarslan, Istanbul Florence Nightingale Hospital, Istanbul, Türkiye

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