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CASE REPORT article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1480363
This article is part of the Research Topic Case Reports in Heart Surgery: 2024 View all 10 articles

A usual procedure in an unusual situation: a patient with a rare Ehlers Danlos/Osteogenesis Imperfecta overlap undergoing Aortic Valve Replacement

Provisionally accepted
Nicolas Nunez Nicolas Nunez 1,2*Andres Felipe Amado-Olivares Andres Felipe Amado-Olivares 1Andres Felipe Jimenez-Ordonez Andres Felipe Jimenez-Ordonez 1,2Carlos Obando Carlos Obando 1Tomas Chalela Tomas Chalela 1Julian Senosiain Julian Senosiain 1Nestor Sandoval Nestor Sandoval 1Jaime Camacho-Mackenzie Jaime Camacho-Mackenzie 1Carlos Andres Villa-Hincapié Carlos Andres Villa-Hincapié 1
  • 1 Cardioinfantil Foundation, Institute of Cardiology, Bogotá, Colombia
  • 2 Rosario University, Bogotá, Bogota, Colombia

The final, formatted version of the article will be published soon.

    Connective tissue disorders are known to cause cardiac and vascular complications. We present the case of a 37-year-old female patient with a rare Ehlers Danlos/Osteogenesis Imperfecta Overlap Syndrome, referred to cardiac surgery with aortic valve regurgitation, who underwent a successful Biological Surgical Aortic Valve Replacement (SAVR). A multidisciplinary, patient-centered, heart-team approach is essential in managing patients with rare genetic disorders to optimize postoperative outcomes. Adult cardiac surgeons must become familiar with genetic syndromes and their implications for improving perioperative outcomes.

    Keywords: aortic valve replacement, Ehlers-danlos, Osteogenesis Imperfecta, Biological SAVR, Genetic syndrome

    Received: 13 Aug 2024; Accepted: 06 Feb 2025.

    Copyright: © 2025 Nunez, Amado-Olivares, Jimenez-Ordonez, Obando, Chalela, Senosiain, Sandoval, Camacho-Mackenzie and Villa-Hincapié. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Nicolas Nunez, Cardioinfantil Foundation, Institute of Cardiology, Bogotá, Colombia

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