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CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1480363
This article is part of the Research Topic Case Reports in Heart Surgery: 2024 View all 12 articles
A usual procedure in an unusual situation: a patient with a rare Ehlers Danlos/Osteogenesis Imperfecta overlap undergoing Aortic Valve Replacement
Provisionally accepted
Nicolas Nunez 1,2*
Andres Felipe Amado-Olivares 1
Andres Felipe Jimenez-Ordonez 1,2 Carlos Obando 1 Tomas Chalela 1 Julian Senosiain 1 Nestor Sandoval 1 Jaime Camacho-Mackenzie 1 Carlos Andres Villa-Hincapié 1- 1 Cardioinfantil Foundation, Institute of Cardiology, Bogotá, Colombia
- 2 Rosario University, Bogotá, Bogota, Colombia
Connective tissue disorders are known to cause cardiac and vascular complications. We present the case of a 37-year-old female patient with a rare Ehlers Danlos/Osteogenesis Imperfecta Overlap Syndrome, referred to cardiac surgery with aortic valve regurgitation, who underwent a successful Biological Surgical Aortic Valve Replacement (SAVR). A multidisciplinary, patient-centered, heart-team approach is essential in managing patients with rare genetic disorders to optimize postoperative outcomes. Adult cardiac surgeons must become familiar with genetic syndromes and their implications for improving perioperative outcomes.
Keywords: aortic valve replacement, Ehlers-danlos, Osteogenesis Imperfecta, Biological SAVR, Genetic syndrome
Received: 13 Aug 2024; Accepted: 06 Feb 2025.
Copyright: © 2025 Nunez, Amado-Olivares, Jimenez-Ordonez, Obando, Chalela, Senosiain, Sandoval, Camacho-Mackenzie and Villa-Hincapié. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Nicolas Nunez, Cardioinfantil Foundation, Institute of Cardiology, Bogotá, Colombia
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