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CASE REPORT article

Front. Cardiovasc. Med.
Sec. Cardio-Oncology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1480310
This article is part of the Research Topic Case Reports in Cardio-Oncology: 2024 View all 7 articles

Cancer-Associated Thoracic Aorta Arterial Thrombosis: Case Report and Review of the Literature

Provisionally accepted
Miguel Borregón Miguel Borregón *María Valero María Valero Asia Ferrández Asia Ferrández Álvaro Muñoz Álvaro Muñoz Carmen Roque Carmen Roque Javier-David Benítez-Fuentes Javier-David Benítez-Fuentes
  • Hospital General Universitario de Elche, Elche, Spain

The final, formatted version of the article will be published soon.

    Background: Arterial thrombosis is an uncommon complication in cancer patients, often overshadowed by venous thromboembolic events. Its occurrence in patients with solid tumors on active antineoplastic treatment poses a significant clinical challenge.Key Clinical Question: Given the lack of consensus on the optimal therapy for arterial thrombosis in cancer patients, the best practices for managing an aortic thrombus, and the benefit of low molecular weight heparin (LMWH) must be reviewed.We present the case of a 70-year-old female with stage IVA lung adenocarcinoma who developed an aortic thrombus during chemo-immunotherapy. The thrombus was successfully treated with LMWH, avoiding further complications, and allowing for the continuation of her cancer therapy.This case highlights the importance of early detection and management of arterial thrombus in cancer patients. LMWH proved effective in resolving the thrombus, underscoring its role in managing such complications.

    Keywords: cancer-associated thrombosis (CAT), Venous thromboembolism (VTE) Data availability statement Deep Venous Thrombosis, Arterial thromboembolism (ATE), cancer biology, Small Cell Lung Carcinoma, Cisplatin

    Received: 13 Aug 2024; Accepted: 07 Jan 2025.

    Copyright: © 2025 Borregón, Valero, Ferrández, Muñoz, Roque and Benítez-Fuentes. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Miguel Borregón, Hospital General Universitario de Elche, Elche, Spain

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