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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. General Cardiovascular Medicine
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1406890

The relationship between negative psychological state and quality of life among cardiovascular disease patients in China: The masking effect of abnormal dietary behavior

Provisionally accepted
Qingning Chang Qingning Chang 1Haibo Ma Haibo Ma 1Can Zhang Can Zhang 1Xin Li Xin Li 1Lina Ha Lina Ha 1*Yibo Wu Yibo Wu 2*
  • 1 Ningxia Medical University, Yinchuan, China
  • 2 Peking University, Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Background: It is well known that abnormal dietary behavior increases the risk for cardiovascular disease especially if the person is depressed and/or anxious. The purpose of this study was to construct a moderated mediation model to explore the roles of abnormal dietary behavior and family health in the mechanism through which depression/anxiety influences Quality of life (QoL) in patients with cardiovascular disease.Methods: A field survey was conducted in China and ultimately included 730 patients with cardiovascular disease aged 20-60 years. Data were collected using the Europe Quality of five-dimensional five-level questionnaire, Short-Form of the Eating Behavior Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and the Chinese version of the short-form of the Family Health Scale. All data were analyzed using SPSS Statistics 23.0.Results: (1) Depression was negatively associated with QoL (r=-0.386/-0.230, p<0.001), and was positively correlated with abnormal dietary behavior (r=0.377, p<0.001). Anxiety was negatively associated with QoL (r=-0.383/-0.231, p<0.001), and was positively correlated with abnormal dietary behavior (r=0.333, p<0.001). Abnormal dietary behavior was negatively correlated with QoL (r=-0.077/-0.119, p=0.039/0.001). (2) In the mediation model, abnormal dietary behavior only had a masking effect on the relationship between depression and QoL, with a mediating effect size of 7.18%. The mediating effect of abnormal dietary behavior between anxiety and QoL was not significant. (3) The mediating effect size of abnormal dietary behavior between depression/anxiety and QoL increased to 14.77% and 13.57% in unhealthy families. The above masking mediation effect was not significant in healthy families.Conclusions: Abnormal dietary behavior positively mediated the relationship between depression and QoL and attenuated the negative effect of depression on QoL in patients with cardiovascular disease. The masking mediating effect of abnormal dietary behavior between depression/anxiety and QoL was stronger for patients in unhealthy families.

    Keywords: negative psychological state, abnormal dietary behavior, Quality of Life, Family Health, cardiovascular disease, * p<0.05, ** P<0.01, *** p<0.001

    Received: 14 May 2024; Accepted: 27 Jan 2025.

    Copyright: © 2025 Chang, Ma, Zhang, Li, Ha and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Lina Ha, Ningxia Medical University, Yinchuan, China
    Yibo Wu, Peking University, Beijing, 100871, Beijing Municipality, China

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