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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1520827

Enhanced recovery in type A aortic dissection evaluating the efficacy and feasibility of early myocardial reperfusion

Provisionally accepted
Tianyu Niu Tianyu Niu Zhishuo Liu Zhishuo Liu Yu Liu Yu Liu Zhonglu Yang Zhonglu Yang Yuguang Ge Yuguang Ge Lu Wang Lu Wang Lin Xia Lin Xia *Hui Jiang Hui Jiang *
  • Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China

The final, formatted version of the article will be published soon.

    Background: This study investigates the feasibility and early outcomes of early myocardial reperfusion in patients with type A aortic dissection (TAAD), evaluating its effectiveness and potential benefits compared to traditional cardioplegic arrest techniques. Methods: A retrospective analysis was conducted on 168 patients diagnosed with TAAD who underwent surgery at the General Hospital of the Northern Theater Command in China from January 2021 to July 2024. Patients were divided into two groups: early myocardial reperfusion (EMR group, n=66) and cardioplegic arrest (CA group, n=102). Perioperative outcomes were compared between the groups. Results: Early myocardial reperfusion significantly reduced ventilation time 23.08 (18.21,66.74) hours vs. 48.58 (19.18,122.97) hours, P<0.05], ICU stay time [58.80 (21.20,126.68) hours vs. 84.86 (41.12,168.81) hours, P<0.05], and hospitalization time [13.00 (10.00,16.00) days vs. 15.00 (11.75,19.00) days, P<0.05] compared to the CA group. There was no significant difference in hospital costs, first-hour chest tube drainage, left ventricular ejection fraction, or postoperative adverse events between the groups, except for the rate of CRRT treatment, where the EMR group had significantly fewer patients requiring postoperative CRRT (10.6% vs. 23.5%, P<0.05). Conclusion: This study demonstrates that early myocardial reperfusion is a feasible and effective technique for TAAD, offering considerable advantages in reducing ventilation time, ICU stay, hospitalization duration and postoperative renal insufficiency.

    Keywords: Type a aortic dissection, early myocardial reperfusion, cardioplegic arrest, Perioperative outcomes, cardiovascular surgery

    Received: 31 Oct 2024; Accepted: 23 Dec 2024.

    Copyright: © 2024 Niu, Liu, Liu, Yang, Ge, Wang, Xia and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Lin Xia, Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
    Hui Jiang, Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.