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MINI REVIEW article

Front. Cardiovasc. Med.
Sec. General Cardiovascular Medicine
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1506836

The function of miRNAs in the immune system's inflammatory reaction to heart failure

Provisionally accepted
Kadierya Yibulayin Kadierya Yibulayin *Maidinaimu Abulizi Maidinaimu Abulizi
  • Xinjiang Medical University, Ürümqi, China

The final, formatted version of the article will be published soon.

    【Abstract】Heart failure is the end stage of cardiovascular disease, with high morbidity and mortality rates worldwide. Heart failure is associated with long-term and insufficient inhibition of inflammatory response. miRNA is a class of endogenous, non-coding, single-stranded small RNA molecules, that can regulate gene expression through translational inhibition or degradation of targeted mRNA, widely regulate myocardial remodeling, inflammatory response, and other pathological processes, and play an important regulatory role in the occurrence and development of cardiovascular diseases. This article reviews the role of miRNA in the inflammatory response in heart failure.

    Keywords: miRNA, Inflammation, TLR4, NF-κB, Heart Failure

    Received: 08 Oct 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Yibulayin and Abulizi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Kadierya Yibulayin, Xinjiang Medical University, Ürümqi, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.