Skip to main content

REVIEW article

Front. Cardiovasc. Med.
Sec. Cardiovascular Imaging
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1504063
This article is part of the Research Topic Revolutionizing Cardiovascular Diagnosis: Advances in Functional Imaging Technologies View all 4 articles

Prognostic Implication of Right Ventricular-Pulmonary Artery Coupling in Valvular Heart Disease

Provisionally accepted
Zhenni Wu Zhenni Wu 1,2,3Mingxing Xie Mingxing Xie 1,2,3Li Zhang Li Zhang 1,2,3Qing He Qing He 1,2,3Lang Gao Lang Gao 1,2,3Mengmeng Ji Mengmeng Ji 1,2,3Yixia Lin Yixia Lin 1,2,3Yuman Li Yuman Li 1,2,3*
  • 1 Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • 2 Clinical Research Center for Medical Imaging in Hubei Province; Wuhan, China, Wuhan, China
  • 3 Hubei Province Key Laboratory of Molecular Imaging; Wuhan, China, Wuhan, China

The final, formatted version of the article will be published soon.

    Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RV-PA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs. RV-PA uncoupling has been shown to be associated with poor outcomes in VHD. This review summarizes the prognostic significance of RV-PA coupling in patients with VHD.Recent studies have found that pre-TAVR RV-PA coupling is predictive of cardiovascular death. Meucci et al.(36) studied 900 patients who underwent TAVR at 2 tertiary centers to evaluate the

    Keywords: right ventricular-pulmonary artery coupling1, valvular heart disease2, pulmonary hypertension3, congenital heart defect4, right ventricular function5, clinical utility6

    Received: 30 Sep 2024; Accepted: 20 Dec 2024.

    Copyright: © 2024 Wu, Xie, Zhang, He, Gao, Ji, Lin and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yuman Li, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.