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REVIEW article

Front. Cardiovasc. Med.
Sec. General Cardiovascular Medicine
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1502620
This article is part of the Research Topic Obesity and Cardiovascular Disease View all 4 articles

Effect of physical exercise on metabolism in patients with atrial fibrillation

Provisionally accepted
Yutong Wang Yutong Wang 1*Sixian Weng Sixian Weng 2Chenxi Xia Chenxi Xia 3TAO XU TAO XU 4Xinyang Song Xinyang Song 3Fang Wang Fang Wang 3*
  • 1 Chinese Academy of Medical Sciences and Peking Union Medical College, Dongcheng, China
  • 2 Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
  • 3 Beijing Hospital, Peking University, Beijing, Beijing Municipality, China
  • 4 National Center of Gerontology, Institute of Geriatrics, Beijing Hospital, Peking University, Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Atrial fibrillation (AF), the most prevalent cardiac arrhythmia, is closely linked to metabolic dysfunctions, including obesity, diabetes, and dyslipidemia. These lead to pathological changes in myocardial metabolism and mitochondrial energy metabolism, thereby aggravating AF's incidence and severity. This review introduces the role of metabolic dysfunctions in exacerbating AF, assesses the therapeutic potential of physical exercise and investigates it as a non-pharmacological intervention to alleviate these metabolic disturbances. Evidence suggests that regular physical activity not only enhances metabolic profiles but also reduces the frequency of AF episodes and improves overall cardiovascular health. At the same time, the review emphasizes the need for individualized exercise regimens, individualized to the metabolic and cardiac conditions of each patient to optimize benefits and minimize risks. Additionally, it calls for more basic studies and large-scale clinical trials to establish and refine evidencebased exercise guidelines specific to AF management.

    Keywords: physical exercise, Atrial Fibrillation, Metabolism, physical activity, metabolic dysfunction

    Received: 27 Sep 2024; Accepted: 06 Dec 2024.

    Copyright: © 2024 Wang, Weng, Xia, XU, Song and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yutong Wang, Chinese Academy of Medical Sciences and Peking Union Medical College, Dongcheng, China
    Fang Wang, Beijing Hospital, Peking University, Beijing, 100730, Beijing Municipality, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.