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SYSTEMATIC REVIEW article

Front. Cardiovasc. Med.
Sec. Heart Valve Disease
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1489674
This article is part of the Research Topic Mitral Valve Disease: In Memoriam Adrian Chester View all articles

The Impact of Pulmonary Hypertension on Prognosis in Moderate-to-Severe Mitral Regurgitation Patients Treated with Transcatheter Edge-to-Edge Mitral Valve Repair: A Comprehensive Meta-Analysis

Provisionally accepted
Zhili Wei Zhili Wei *Xinquan Shao Xinquan Shao *Zhijing An Zhijing An *Yixuan Chang Yixuan Chang *Shidong Liu Shidong Liu *Ziran Luo Ziran Luo *Yang Chen Yang Chen *Bing Song Bing Song *
  • Lanzhou University, Lanzhou, China

The final, formatted version of the article will be published soon.

    Methods: As of August 2024, relevant studies were identified through searches of the PubMed, Cochrane Library, Web of Science, and Embase databases. A comprehensive screening process was conducted, with quality assessment performed utilizing the Newcastle Ottawa Scale (NOS). Data analysis was carried out using Stata17.0 software, generating forest plots, funnel plots, Egger's test, and sensitivity analysis plots to analyze heterogeneity and publication bias. Odds ratios (OR) and standardized mean differences (SMD) were calculated for dichotomous and continuous variables, respectively, each presented with a 95% confidence interval (CI).Results: A total of 10 studies involving 28,404 patients were included, with all articles achieving a NOS score of ≥ 7. The outcome indicators were as follows: 2-year all-

    Keywords: cause mortality [OR=2.06, 95%CI(1.49, 2.84), p<0.01, I ² =79.9%], heart failure rehospitalization rate [OR=1.56, 95%CI(1.29,1.76), p<0.01, I²=41.7%], 30-day all-cause mortality [OR=2.10, 95%CI(1.78,2.47), p<0.01, I ² =0%], cardiogenic mortality [OR=2.00, 95%CI (1.61,2.49), p<0.01, I²=0%], and length of hospital stay [OR=0.17, 95%CI(0.14,0.20), p<0.01, I²=0%]

    Received: 01 Sep 2024; Accepted: 20 Dec 2024.

    Copyright: © 2024 Wei, Shao, An, Chang, Liu, Luo, Chen and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Zhili Wei, Lanzhou University, Lanzhou, China
    Xinquan Shao, Lanzhou University, Lanzhou, China
    Zhijing An, Lanzhou University, Lanzhou, China
    Yixuan Chang, Lanzhou University, Lanzhou, China
    Shidong Liu, Lanzhou University, Lanzhou, China
    Ziran Luo, Lanzhou University, Lanzhou, China
    Yang Chen, Lanzhou University, Lanzhou, China
    Bing Song, Lanzhou University, Lanzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.