AUTHOR=Misawa Toru , Lee Tetsumin , Ashikaga Takashi , Nozato Toshihiro , Yonetsu Taishi , Sasano Tetsuo 

TITLE=Case Report: Drug-coated balloon after intravascular lithotripsy for the treatment of severely calcified de novo coronary artery lesion

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1470785

DOI=10.3389/fcvm.2024.1470785

ISSN=2297-055X

ABSTRACT=<p>In patients undergoing percutaneous coronary intervention (PCI), severely calcified lesions remain a great challenge even in the drug-eluting stent (DES) era. Intravascular lithotripsy (IVL) is effective for modification of severely calcified lesions prior to DES implantation. However, the efficacy of PCI with drug-coated balloon (DCB) following IVL has not been fully elucidated. Here, we present a case of severely calcified <italic>de novo</italic> coronary artery lesion successfully underwent PCI with DCB following IVL under optical coherence tomography (OCT) guidance as well as mid-term follow-up OCT. DCB following IVL might be a potential revascularization strategy for patients with heavily calcified <italic>de novo</italic> coronary artery lesions.</p>