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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1447487
This article is part of the Research Topic Insights in Heart Surgery: 2023 View all 4 articles

Pediatric RVOT reconstruction with ePTFE trileaflet valved conduits: a dual-center Chinese study

Provisionally accepted
Kai Luo Kai Luo 1Qiliang Zhang Qiliang Zhang 2Xiao-Yang Zhang Xiao-Yang Zhang 1Zi-Jie Zhou Zi-Jie Zhou 1Yan-Jun Pan Yan-Jun Pan 1Zhong-Qun Zhu Zhong-Qun Zhu 1Qiang Chen Qiang Chen 1Jinghao Zheng Jinghao Zheng 1XIAOMIN HE XIAOMIN HE 1*Wei Zhang Wei Zhang 1
  • 1 Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine,, Shanghai, China
  • 2 Fujian Medical University, Fuzhou, Fujian Province, China

The final, formatted version of the article will be published soon.

    Objective: This study aims to assess the early to mid-term clinical efficacy of expanded polytetrafluoroethylene (ePTFE) trileaflet valved conduits in pediatric right ventricular outflow tract reconstruction for congenital heart disease. Methods: We conducted a retrospective analysis of pediatric patients who underwent right ventricular outflow tract (RVOT) reconstruction using ePTFE trileaflet valved conduits at two cardiac centers in China, between January 2017 and June 2023. The main assessment criterion was the functionality of the prosthetic pulmonary valve conduit. Results: A total of 162 pediatric patients were included, with follow-up periods ranging from 0.1 to 5 years post-discharge, and a median follow-up duration of 1 year (interquartile range: 1, 2). Three patients (1.9%) required re-operation due to conduit obstruction. During follow-up, pulmonary valve flow velocities were recorded as <3 m/s in 134 patients (82.7%), between 3 and 4 m/s in 24 patients (14.8%), and >4 m/s in 4 patient (2.5%). Mild pulmonary valve regurgitation was noted in 148 patients (91.4%), and moderate pulmonary valve regurgitation was noted in 14 patients (8.6%), with no instances of more than moderate pulmonary valve regurgitation. Conclusion: The ePTFE trileaflet valved conduit, known for its accessibility and simplicity in manufacturing, demonstrates favorable early to mid-term clinical outcomes in pediatric RVOT reconstruction.

    Keywords: polytetrafluoroethylenep, trileaflet valve conduits, pediatric, Right ventricular outflow tract reconstruction, Pulmonary valve regurgitation

    Received: 11 Jun 2024; Accepted: 03 Sep 2024.

    Copyright: © 2024 Luo, Zhang, Zhang, Zhou, Pan, Zhu, Chen, Zheng, HE and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: XIAOMIN HE, Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine,, Shanghai, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.