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SYSTEMATIC REVIEW article

Front. Cardiovasc. Med.
Sec. Heart Failure and Transplantation
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1435677

The Association Between Pulse Wave Velocity and Heart Failure: A Systematic Review and Meta-Analysis

Provisionally accepted
Zahra Esmaeili Zahra Esmaeili 1Pegah Bahiraie Pegah Bahiraie 2Zahra Vaziri Zahra Vaziri 3Alireza Azarboo Alireza Azarboo 1Amir Hossein Behnoush Amir Hossein Behnoush 1Amirmohammad Khalaji Amirmohammad Khalaji 1Aida Bazrgar Aida Bazrgar 4Pouya Tayebi Pouya Tayebi 5Naghmeh Ziaie Naghmeh Ziaie 6*
  • 1 School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • 2 Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • 3 Student Research Committee, Babol University of Medical Sciences, Babol, Iran
  • 4 Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Shiraz, Iran
  • 5 Department of Vascular and Endovascular Surgery, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
  • 6 Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

The final, formatted version of the article will be published soon.

    The arterial stiffness measured by pulsed wave velocity (PWV) is associated with heart failure (HF).However, the effectiveness of arterial stiffness and PWV as prognostic indicators in patients with HFpEF and HFrEF is still unclear. In this systematic review and meta-analysis, we synthesized the prognostic value of PWV and arterial stiffness in HF patients.Four databases, including Embase, PubMed, Scopus, and Web of Science, were systematically searched for published studies assessing the relationship between PWV and HF from inception up to August 31, 2023. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. The standardized mean difference (SMD) and their corresponding 95% confidence intervals (CI) were used to compare PWV in HF (HFrEF and HFpEF) and controls. Meta-regressions based on age, year of publication, sample size, and gender (male percentage) were also conducted.Patients with HF exhibit significantly higher arterial stiffness, as indicated by PWV, compared to the normal population. However, this association was not significant between HFrEF and HFpEF patients.Future research is warranted to establish the potential prognostic role of PWV in HF.

    Keywords: arterial stiffness, Pulsed wave velocity, Heart Failure, Systematic review, Meta-analysis

    Received: 20 May 2024; Accepted: 02 Jul 2024.

    Copyright: © 2024 Esmaeili, Bahiraie, Vaziri, Azarboo, Behnoush, Khalaji, Bazrgar, Tayebi and Ziaie. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Naghmeh Ziaie, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.