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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Cardiovascular Epidemiology and Prevention
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1429513

Prevalence and the risk factors of mortality among heart failure patients in low resource setting hospitals. A multicenter prospective observational study

Provisionally accepted
Firomsa Bekele Firomsa Bekele 1*Tadesse Sheleme Tadesse Sheleme 2Tesfaye Tsegaye Tesfaye Tsegaye 2S. Angala Parameswari S. Angala Parameswari 2Manjoor A. Syed Manjoor A. Syed 2Lalise Tafese Lalise Tafese 3Wubishet Gezimu Wubishet Gezimu 4
  • 1 Wollega University, Nekemte, Ethiopia
  • 2 Department of Pharmacy, College of Health Sciences, Mettu university, Mettu, Ethiopia
  • 3 Department of Health Informatics, College of Health Sciences, Mattu University, Mattu, Ethiopia
  • 4 Department of Nursing, College of Health Sciences, Mattu University, Mattu, Ethiopia

The final, formatted version of the article will be published soon.

    Background: Heart failure is a significant worldwide health problem leads to mortality. Therefore, the study was aimed to evaluate treatment outcomes and associated factors of heart failure patients who were admitted to hospitals in the southwest of Ethiopia. Methods and participants: A multicenter prospective observational study was conducted from February 1, 2021 to August1, 2021. The Drug therapy problems were assessed as per Cipolle, Strands and Morley’s drug therapy problems classification method. The drug therapy was registered by using drug related problem registration format. The results of logistic regression analysis was interpreted as crude odds ratio and adjusted odds ratio at 95%CI to determine the association between dependent and independent variables. Results: In our study settings, a total of 205 (85.1%) heart failure patients were improved and 36 (14.9%) of them were died at hospital discharge. Being > 65 years (AOR=7.14, 95CI%: 2.04-.25.01, P=0.002), a previous hospitalization (AOR=6.20, 95CI%:1.81-21.21, P=0.004), and the presence of medication related problems (AOR=3.65, 95CI%:1.13-11.73, P=0.03) were the predictor of mortality. Conclusion: The prevalence of in hospital mortality among heart failure patients was found to be high. Previous hospitalization, older ages and the presence of drug therapy problems were the predictors of mortality among heart failure patients. Therefore, proper attention should be given to the management of elderly and re-admitted heart failure patients in addition to their regular care. In addition, hospitals should implement clinical pharmacy services to address any drug-related problems.

    Keywords: Heart Failure, Mortality, Associated factors, Ethiopia, Prevalence

    Received: 12 Jun 2024; Accepted: 04 Nov 2024.

    Copyright: © 2024 Bekele, Sheleme, Tsegaye, Parameswari, Syed, Tafese and Gezimu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Firomsa Bekele, Wollega University, Nekemte, Ethiopia

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