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ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Heart Failure and Transplantation
Volume 11 - 2024 |
doi: 10.3389/fcvm.2024.1406511
Dietary fiber intake and all-cause and CVD-cause mortality among HF survivors
Provisionally accepted- Qingyuan People's Hospital, Qingyuan, China
Aim: Heart failure (HF) is a severe manifestation or late stage of various heart diseases.As an anti-inflammatory nutrient, dietary fiber has been shown to be associated with the progression and prognosis of cardiovascular diseases (CVDs). However, little is known about the relationship between dietary fiber intake and mortality in HF survivors.This study evaluated the association of dietary fiber intake and all-cause and CVDscause mortality among HF survivors.Methods: Data of study were extracted from the National Health and Nutrition Examination Survey (NHANES) 1999-2018. Dietary fiber intake information was obtained by 24-h dietary recall interview. Death outcomes were ascertained by linkage to National Death Index (NDI) records through 31 December 2019. Covariates included sociodemographic information, lifestyles, diseases history and laboratory data were extracted from the database. The weighted univariate and multivariate COX proportional hazard models were utilized to explore the association between dietary fiber intake and mortality among HF survivors, with hazard ratios (HRs) and 95% confidence intervals (CIs). Further stratified analyses were performed to explore this association based age, gender, the history of diabetes and dyslipidemia, and duration of HF.Results: A total of 1,510 patients were included. Until December 31, 2019, 859 deaths occurred over a mean follow-up of 70.00 months. After multivariable adjustment, higher dietary fiber intake was associated with the lower risk of all-cause and CVDscause mortality in HF survivors, especially in patients with male, aged<60 years old Dietary fiber intake and all-cause and CVD-cause mortality among HF survivors 3 and with the history of diabetes and dyslipidemia.Conclusion:Among HF survivors, higher dietary fiber intake level may be associated with a good health outcome. More large-scale prospective cohort studies are needed to further explore this benefit relationship.
Keywords: Dietary Fiber, Heart Failure, All-cause mortality, CVD-cause mortality, NHANES
Received: 25 Mar 2024; Accepted: 13 Dec 2024.
Copyright: © 2024 Wang, Ruan and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shulin Wang, Qingyuan People's Hospital, Qingyuan, China
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