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REVIEW article

Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1392702
This article is part of the Research Topic Insights in Coronary Artery Disease: 2023 View all 8 articles

Biomechanical Factors and Atherosclerosis Localization: insights and clinical applications

Provisionally accepted
Elena Bacigalupi Elena Bacigalupi 1Jacopo Pizzicannella Jacopo Pizzicannella 2Gianluca Rigatelli Gianluca Rigatelli 3Luca Scorpiglione Luca Scorpiglione 1Melissa Foglietta Melissa Foglietta 1,4Greta Rende Greta Rende 1Cesare Mantini Cesare Mantini 1Franco Michelino Fiore Franco Michelino Fiore 5Francesco Pelliccia Francesco Pelliccia 6Marco Zimarino Marco Zimarino 1,4*
  • 1 Department of Neuroscience, Imaging and Clinical Sciences, University of Studies G. d'Annunzio Chieti and Pescara, Chieti, Italy
  • 2 Department of Engineering and Geology, G. d'Annunzio University of Chieti and Pescara, Pescara, Italy
  • 3 Ospedali Riuniti Padova Sud Madre Teresa di Calcutta, Padova, Italy
  • 4 SS Annunziata Polyclinic Hospital, Chieti, Chieti, Italy
  • 5 Annunziata Hospital, Cosenza, Calabria, Italy
  • 6 Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Lazio, Italy

The final, formatted version of the article will be published soon.

    Elena Bacigalupi has nothing to disclose Jacopo Pizzicannella has nothing to disclose Luca Scorpiglione has nothing to disclose Gianluca Rigatelli has nothing to disclose Cesare Mantini has nothing to disclose Melissa Foglietta has nothing to disclose Greta Rende has nothing to disclose Franco M Fiore has nothing to disclose Francesco Pelliccia has nothing to disclose Marco Zimarino has nothing to disclose The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.• Biomechanical factors contribute to valuable prognostic information beyond anatomical and physiological plaque characteristics in the localization and evolution of coronary atherosclerosis.• Computational fluid dynamics offers clinical applications in the assessment of plaque vulnerability, coronary lesion severity, stent-vessel interactions, and coronary bifurcation complexities.

    Keywords: biomechanics factors, Wall Shear Stress, axial plaque stress, Plaque structural stress, Computational fluid dynamic

    Received: 27 Feb 2024; Accepted: 15 Jul 2024.

    Copyright: © 2024 Bacigalupi, Pizzicannella, Rigatelli, Scorpiglione, Foglietta, Rende, Mantini, Fiore, Pelliccia and Zimarino. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Marco Zimarino, SS Annunziata Polyclinic Hospital, Chieti, Chieti, 66100, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.