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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1388577

A Comparative Study of Femoral Artery and Combined Femoral and Axillary Artery Cannulation in Veno-Arterial Extracorporeal Membrane Oxygenation Patients

Provisionally accepted
Na Jin Na Jin *Xin Pang Xin Pang Shiyang Song Shiyang Song Jin Zheng Jin Zheng Zhimeng Liu Zhimeng Liu Tianxiang Gu Tianxiang Gu Yang Yu Yang Yu
  • The First Affiliated Hospital of China Medical University, Shenyang, China

The final, formatted version of the article will be published soon.

    Objective: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a critical support technique for cardiac surgery patients. This study compares the outcomes of femoral artery cannulation versus combined femoral and axillary artery cannulation in post-cardiotomy VA-ECMO patients. This study aimed to compare the clinical outcomes of critically ill patients post-cardiac surgery under VA-ECMO support using different cannulation strategies. Specifically, the focus was on the impact of femoral artery (FA) cannulation versus combined femoral artery and axillary artery (FA+AA) cannulation on patient outcomes.Methods: Through a retrospective analysis, we compared 51 adult patients who underwent cardiac surgery and received VA-ECMO support based on the cannulation strategy employed-FA cannulation in 27 cases versus FA+AA cannulation in 24 cases.The FA+AA group showed significant advantages over the FA group in terms of the incidence of chronic renal failure (CRF) (37.50% vs. 14.81%, p=0.045), preoperative blood filtration requirement (37.50% vs. 11.11%, p=0.016), decreased platelet count (82.67±44.95 vs. 147.33±108.79, p=0.014), and elevated creatinine (Cr) levels (151.80±60.73 vs. 110.26±57.99, p=0.041), although the two groups had similar 30-day mortality rates (FA group 40.74%, FA+AA group 33.33%). These findings underscore that a combined approach may offer more effective hemodynamic support and better clinical outcomes when selecting an ECMO cannulation strategy.Despite the FA+AA group patients presenting with more preoperative risk factors, this group has exhibited lower rates of complications and faster recovery during ECMO treatment.While there has been no significant difference in 30-day mortality rates between the two cannulation strategies, the FA+AA approach may be more effective in reducing complications and improving limb ischemia. These findings highlight the importance of individualized treatment strategies and meticulous monitoring in managing post-cardiac surgery ECMO patients.

    Keywords: cardiac surgery, VA-ECMO, cannulation strategy, clinical outcomes, Limb ischemia, Individualized treatment, clinical complications, Mortality rate

    Received: 26 Feb 2024; Accepted: 27 Aug 2024.

    Copyright: © 2024 Jin, Pang, Song, Zheng, Liu, Gu and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Na Jin, The First Affiliated Hospital of China Medical University, Shenyang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.