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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1366072

Predictive Value of Percutaneous Peripheral Arterial Compliance T in Left Ventricular Diastolic Function with Coronary Artery Disease

Provisionally accepted
Wenhao Zhang Wenhao Zhang 1,2Guoliang Liang Guoliang Liang 3*Liang Lv Liang Lv 4*Xinxin Gu Xinxin Gu 1*Qiong Zhang Qiong Zhang 2Ankang Liu Ankang Liu 2*Jiangwei Ma Jiangwei Ma 1,2*
  • 1 Jinzhou Medical University Shanghai Fengxian Postgraduate Training Base, Shanghai, China
  • 2 Fengxian District Central Hospital, Shanghai, Shanghai Municipality, China
  • 3 Anhui University of Science and Technology, Huainan, China
  • 4 Xi'an Central Hospital, Xi'an, Shaanxi Province, China

The final, formatted version of the article will be published soon.

    Background: Diastolic dysfunction emerges early in patients with cardiac insufficiency and is prevalent, underscoring the importance of its early identification and intervention in the prevention of heart failure. The study leverages the convenience and accuracy of measuring peripheral arterial sclerosis to facilitate the early detection of diastolic dysfunction, which is instrumental in mitigating and delaying the onset and progression of heart failure, holding significant clinical relevance.: This research enrolled 556 patients suspected of experiencing Acute Coronary Syndrome (ACS) and stratified them into Groups A, B, C, and D according to the severity of coronary artery stenosis. The diastolic function of the left ventricle was indicated by the relaxation time constant, denoted as T value, which measures the temporal span from the peak rate of left ventricular pressure rise (dp/dt) to the end-diastolic pressure. Results: The T value of the left ventricle demonstrated a significant correlation with the Gensini Score and the T values across various peripheral arteries (P<0.01). Pearson correlation analysis showed that the average value of peripheral arterial compliance indices in Group C and the average value of peripheral arterial compliance indices in Group D had a significant correlation with LV-T. At the same time, linear analysis of the average values of peripheral arterial compliance indices in both groups revealed that the average compliance indices in Groups C and D had a linear correlation with their LV-T (P<0.05).When coronary artery stenosis exceeds 50%, the changes in peripheral arterial T values are significantly correlated with changes in LV-T. Conclusions: When coronary artery stenosis exceeds 50%, there is a decrease in peripheral artery compliance, showing a positive correlation with changes in left ventricular diastolic function.Measuring this compliance might offer an early diagnostic tool for assessing diastolic function.

    Keywords: Arterial elasticity index, Left ventricular dysfunction, Coronary Artery Disease, Heart Failure，Ejection Fraction, ejection fraction

    Received: 05 Jan 2024; Accepted: 24 Oct 2024.

    Copyright: © 2024 Zhang, Liang, Lv, Gu, Zhang, Liu and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Guoliang Liang, Anhui University of Science and Technology, Huainan, China
    Liang Lv, Xi'an Central Hospital, Xi'an, 710003, Shaanxi Province, China
    Xinxin Gu, Jinzhou Medical University Shanghai Fengxian Postgraduate Training Base, Shanghai, China
    Ankang Liu, Fengxian District Central Hospital, Shanghai, 201400, Shanghai Municipality, China
    Jiangwei Ma, Jinzhou Medical University Shanghai Fengxian Postgraduate Training Base, Shanghai, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.