AUTHOR=Djokovic Aleksandra , Krljanac Gordana , Matic Predrag , Zivic Rastko , Djulejic Vuk , Marjanovic Haljilji Marija , Popovic Dusan , Filipovic Branka , Apostolovic Svetlana 

TITLE=Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1260478

DOI=10.3389/fcvm.2023.1260478

ISSN=2297-055X

ABSTRACT=<p>Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.</p>