AUTHOR=Huang Jing-bin , Lu Chang-chao , Wen Zhao-ke , Yang Jian-rong , Li Jun-jun 

TITLE=Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1217148

DOI=10.3389/fcvm.2023.1217148

ISSN=2297-055X

ABSTRACT=<sec><title>Introduction</title><p>We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery.</p></sec><sec><title>Methods</title><p>This was a retrospective study of patients with left-sided infective endocarditis and symptomatic neurological complications before surgery undergoing cardiac surgery between January 2006 and November 2022 at our hospital.</p></sec><sec><title>Results</title><p>Eight hundred thirty-two patients were divided into group with symptomatic neurological complications before surgery (<italic>n</italic> = 112) and without symptomatic neurological complications before surgery (<italic>n</italic> = 720). There were 48 operative deaths (5.4%). Univariate and multivariate analyses showed that symptomatic neurological complications before surgery is statistically significantly associated with in-hospital mortality following cardiac surgery and prolonged intubation time.</p></sec><sec><title>Conclusions</title><p>Our study showed that symptomatic neurological complications before surgery are associated with increased in-hospital mortality following cardiac surgery and prolonged intubation time.</p></sec>