AUTHOR=Akiki Elias , Ahmad Ali , El-Am Edward A. , Casanegra Ana I. , Klarich Kyle W. , Kurmann Reto TITLE=Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=10 YEAR=2023 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1208190 DOI=10.3389/fcvm.2023.1208190 ISSN=2297-055X ABSTRACT=

An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.