AUTHOR=Dong Yi-ming , Liu Xia , Yang Chen-teng , Qi Qian , Shi Wei-bo , Li Ying-min , Zuo Min , Wang Song-jun , Bi Hai-tao , Ma Ru-fei , Zhang Guo-zhong , Cong Bin 

TITLE=Case report: Myocarditis following COVID-19 protein subunit vaccination

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.970045

DOI=10.3389/fcvm.2022.970045

ISSN=2297-055X

ABSTRACT=<p>We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of lymphocytes and monocytes in the myocardium of the left and right ventricular walls associated with myocyte degeneration and necrosis. This report highlights the details of clinical presentations and autopsy findings of myocarditis after ZF2001 (RBD-subunit vaccine) vaccination. The correlation between vaccination and death due to myocarditis is discussed.</p>