AUTHOR=Li Rui , Ma Fei , Guan Han Xiong , Pan Yue Ying , Liu Li Gang , Wang Dao Wen , Wang Hong 

TITLE=Case Report: Giant Congenital Left Atrial Appendage Aneurysm Presenting With Acute Massive Cerebral Infarction and Refractory Atrial Fibrillation: A Case Report and Literature Review

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.888825

DOI=10.3389/fcvm.2022.888825

ISSN=2297-055X

ABSTRACT=<sec><title>Background</title><p>Congenital left atrial appendage aneurysm (LAAA) is a rare cardiac anomaly with a variety of presentations, from being asymptomatic to potentially serious complications such as systemic thromboembolism and atrial tachyarrhythmia.</p></sec><sec><title>Case Presentation</title><p>We report a case of congenital giant LAAA in a 35-year-old man presenting with acute massive cerebral infarction and atrial fibrillation (AF) with rapid ventricular rate. The AF was refractory to conventional antiarrhythmic agents, such as amiodarone and electrical cardioversion, but restored and maintained sinus rhythm after surgical resection of LAAA. The patient remained free of events and was in sinus rhythm during half-year follow-up.</p></sec><sec><title>Conclusion</title><p>Giant LAAA has the potential causing serious complications and should be managed surgically in most cases.</p></sec>