AUTHOR=Gao Feng , Shi Zepeng , He Xuezhi , Gao Yang , Zhuang Xijing , Shi Lei , Wang Wenjun , Liu Wei 

TITLE=The short-term efficacy of adventitial inversion with graft eversion anastomosis for the reconstruction of the aortic sinus in the root treatment of aortic dissection

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.845040

DOI=10.3389/fcvm.2022.845040

ISSN=2297-055X

ABSTRACT=<sec><title>Background</title><p>The surgical approaches for a mildly affected aortic sinus (AS) are varied and controversial. Here, the AS was reconstructed using the extended adventitial inversion with graft eversion anastomosis technique before its perioperative and short-term efficacy was compared with that of the vascular grafts that wrap the aortic wall and the right atrial shunt technique, providing a new basis for surgical management strategies.</p></sec><sec><title>Method</title><p>A total of 101 patients with mildly affected AS were enrolled in the clinical trial. The extended adventitial inversion suture and the graft eversion anastomosis technique was performed in group A. Aorta wrapping and the right atrial shunt technique were performed in group B. The primary endpoints were reoperation-related events and fatal events related to the aorta, while the secondary endpoints were the duration of surgery and structural changes in the aortic root. Cardiac ultrasound and aortic computed tomography angiography examinations were performed before surgery, 2 weeks after surgery, and 1 year after surgery.</p></sec><sec><title>Results</title><p>Compared to group B (<italic>n</italic> = 56), group A (<italic>n</italic> = 36) had a significantly shorter duration of surgery (the time from skin incision to skin closure) and a reduced time from shutdown to skin closure (<italic>P</italic> &lt; 0.05). Cardiovascular ultrasound examinations performed at follow-up 12 months after surgery and 2 weeks after surgery revealed a significant increase in the diameter of the aortic sinotubular junction (STJ) of group B (<italic>n</italic> = 50) (<italic>P</italic> &lt; 0.05). The extended adventitial inversion suture and the graft eversion anastomosis technique (<italic>n</italic> = 33) performed better than Aorta wrapping and the right atrial shunt technique in terms of persistence of the false lumen closure effect, anastomotic leakage, and reduction in aortic valve (<italic>P</italic> &lt; 0.05), and there was a significant difference between the two groups in terms of the incidence of events related to reoperation (<italic>P</italic> &lt; 0.05).</p></sec><sec><title>Conclusion</title><p>Compared with the aorta wrapping and the right atrial shunt technique, the extended adventitial inversion suture and the graft eversion anastomosis technique allow shortening of the operation time and preventing near-term dilation of the STJ, with improved safety and an improved short-term surgical effect.</p></sec>