AUTHOR=Spione Francesco , Arevalos Victor , Gabani Rami , Sabaté Manel , Brugaletta Salvatore TITLE=Coronary Microvascular Angina: A State-of-the-Art Review JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.800918 DOI=10.3389/fcvm.2022.800918 ISSN=2297-055X ABSTRACT=

Up to 60–70% of patients, undergoing invasive coronary angiography due to angina and demonstrable myocardial ischemia with provocative tests, do not have any obstructive coronary disease. Coronary microvascular angina due to a dysfunction of the coronary microcirculation is the underlying cause in almost 50% of these patients, associated with a bad prognosis and poor quality of life. In recent years, progress has been made in the diagnosis and management of this condition. The aim of this review is to provide an insight into current knowledge of this condition, from current diagnostic methods to the latest treatments.