AUTHOR=Beyls Christophe , Huette Pierre , Vangreveninge Paul , Leviel Florent , Daumin Camille , Ammar BenAmmar , Touati Gilles , Roger Bouzerar , Caus Thierry , Dupont Hervé , Abou-Arab Osama , Momar Diouf , Mahjoub Yazine 

TITLE=Interchangeability of right ventricular longitudinal shortening fraction assessed by transthoracic and transoesophageal echocardiography in the perioperative setting: A prospective study

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1074956

DOI=10.3389/fcvm.2022.1074956

ISSN=2297-055X

ABSTRACT=<sec><title>Background</title><p>Conventional transthoracic (TTE) and transoesophageal echocardiography (TEE) parameters assessing right ventricle (RV) systolic function are daily used assuming their clinical interchangeability. RV longitudinal shortening fraction (RV-LSF) is a two-dimensional speckle tracking parameter used to assess RV systolic function. RV-LSF is based on tricuspid annular displacement analysis and could be measured with TTE or TEE.</p></sec><sec><title>Objective</title><p>The aim of the study was to determine if RV-LSF<sub>TTE</sub> and RV-LSF<sub>TEE</sub> measurements were interchangeable in the perioperative setting.</p></sec><sec><title>Methods</title><p>Prospective perioperative TTE and TEE echocardiography were performed under general anesthesia during scheduled cardiac surgery in 90 patients. RV-LSF was measured by semi-automatic software. Comparisons were performed using Pearson correlation and Bland-Altman plots. RV-LSF clinical agreement was determined as a range of −5 to 5%.</p></sec><sec><title>Results</title><p>Of the 114 patients who met the inclusion criteria, 90 were included. The mean preoperative RV-LSF<sub>TTE</sub> was 20.4 ± 4.3 and 21.1 ± 4.1% for RV-LSF<sub>TEE.</sub> The agreement between RV-LSF measurements was excellent, with a bias at −0.61 and limits of agreement of −4.18 to 2.97 %. All measurements fell within the determined clinical agreement interval in the Bland-Altman plot. Linear regression analysis showed a high correlation between RV-LSF<sub>TTE</sub> and RV-LSF<sub>TEE</sub> measurement (r = 0.9; confidence interval [CI] 95%: [0.87–0.94], <italic>p</italic> &lt; 0.001).</p></sec><sec><title>Conclusion</title><p>RV-LSF<sub>TTE</sub> and RV-LSF<sub>TEE</sub> measurements are interchangeable, allowing RV-LSF to be a helpful parameter for assessing perioperative changes in RV systolic function.</p></sec><sec><title>NCT</title><p>NCT05404737. <ext-link ext-link-type="uri" xlink:href="https://www.clinicaltrials.gov/ct2/show/NCT05404737" xmlns:xlink="http://www.w3.org/1999/xlink">https://www.clinicaltrials.gov/ct2/show/NCT05404737</ext-link>.</p></sec>