AUTHOR=Thoddi Ramamurthy Muralidharan , Kumar Balakrishnan Vinod , Sunny Sini , Rajkumar Abinayaa , Sundaram Sandhya , Krishnamurthy Preetam , Boopathy Senguttuvan Nagendra , Murali Arunan , Santhosham J. D. Roy , Periandavan Kalaiselvi , Rajasekaran Namakkal S. TITLE=Case report: Metastatic myxoid liposarcoma arising from the right atrium extends as cardiac tamponade—A rare case of atrial oncology JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=9 YEAR=2023 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1046436 DOI=10.3389/fcvm.2022.1046436 ISSN=2297-055X ABSTRACT=

The reported incidence of liposarcomas in ~2,000 cases annually results in about 30% of myxoid liposarcomas. Cardiac myoxid liposarcomas are very rare; their presentation could be cardiac tamponade, due to direct compression of the tumor and/or pericardial effusion. In this report, we describe a patient who presented with pericardial effusion secondary to myoxid liposarcomas from the right atrium, an extremely rare presentation of liposarcomas in the heart. We also present non-invasive imaging through echocardiography, CECT thorax and FDG PET scans, followed by a CT-guided mass biopsy. Histopathology of the right atrial mass demonstrated myxoid liposarcoma positive for the S100 tumor marker.