AUTHOR=Gambahaya Ellise T. , Rana Rimsha , Bagchi Shashwatee , Sharma Garima , Sarkar Sudipa , Goerlich Erin , Cupido Blanche , Mukherjee Monica , Hays Allison G. TITLE=The Role of Multimodality Imaging in HIV-Associated Cardiomyopathy JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=8 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2021.811593 DOI=10.3389/fcvm.2021.811593 ISSN=2297-055X ABSTRACT=

Despite marked advances in therapeutics, HIV infection remains a leading cause of morbidity and mortality worldwide. HIV infection is associated with cardiovascular complications including myocardial dysfunction. The description of HIV-associated cardiomyopathy (HIVAC) has evolved over time from a predominantly dilated cardiomyopathy with systolic dysfunction to one of subclinical diastolic dysfunction. Multimodality cardiovascular imaging plays an integral role in our understanding of the etiology and pathogenesis of HIVAC. Such imaging is also essential in the evaluation of individuals with chronic HIV disease who present with cardiac symptoms, especially of heart failure. In the present review, we will highlight current evidence for the role of multimodality imaging in establishing the diagnosis, etiology and pathophysiology of HIVAC as well as guiding treatment and assessing prognosis.