AUTHOR=Li Jiahui , Zhang Lijun , Wang Yueli , Zuo Huijuan , Huang Rongchong , Yang Xueyao , Han Ye , He Yi , Song Xiantao 

TITLE=Agreement in Left Ventricular Function Measured by Echocardiography and Cardiac Magnetic Resonance in Patients With Chronic Coronary Total Occlusion

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2021.675087

DOI=10.3389/fcvm.2021.675087

ISSN=2297-055X

ABSTRACT=<p><bold>Aims:</bold> To determine the agreement between two-dimensional transthoracic echocardiography (2DTTE) and cardiovascular magnetic resonance (CMR) in left ventricular (LV) function [including end-systolic volume (LVESV), end-diastolic volume (LVEDV), and ejection fraction (LVEF)] in chronic total occlusion (CTO) patients.</p><p><bold>Methods:</bold> Eighty-eight CTO patients were enrolled in this study. All patients underwent 2DTTE and CMR within 1 week. The correlation and agreement of LVEF, LVESV, and LVEDV as measured by 2DTTE and CMR were assessed using Pearson correlation, Kappa analysis, and Bland–Altman method.</p><p><bold>Results:</bold> The mean age of patients enrolled was 57 ± 10 years. There was a strong correlation (<italic>r</italic> = 0.71, 0.90, and 0.80, respectively, all <italic>P</italic> &lt; 0.001) and a moderately strong agreement (Kappa = 0.62, <italic>P</italic> &lt; 0.001) between the two modalities in measurement of LV function. The agreement in patients with EF ≧50% was better than in those with an EF &lt;50%. CTO patients without echocardiographic wall motion abnormality (WMA) had stronger intermodality correlations (<italic>r</italic> = 0.84, 0.96, and 0.87, respectively) and smaller biases in LV function measurement.</p><p><bold>Conclusions:</bold> The difference in measurement between 2DTTE and CMR should be noticed in CTO patients with EF &lt;50% or abnormal ventricular motion. CMR should be considered in these conditions.</p>