AUTHOR=Costa Isabela Bispo Santos da Silva , Andrade Fernanda Thereza de Almeida , Carter Diego , Seleme Vinicius B. , Costa Maycon Santos , Campos Carlos M. , Hajjar Ludhmila Abrahão TITLE=Challenges and Management of Acute Coronary Syndrome in Cancer Patients JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=8 YEAR=2021 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2021.590016 DOI=10.3389/fcvm.2021.590016 ISSN=2297-055X ABSTRACT=

Cancer and cardiovascular disease are the leading causes of mortality in the world. The prevalence of cardiovascular risk factors and coronary artery disease in cancer patients is elevated, and it is associated with high mortality. Several mechanisms, such as the proinflammatory and procoagulant states present in cancer patients, may contribute to these scenarios. Oncological therapy can predispose patients to acute thrombosis, accelerated atherosclerosis and coronary spasm. Treatment decisions must be individualized and based on the cancer history and balancing bleeding and thrombosis risks.