AUTHOR=Li Yi-ming , Tsauo Jia-yu , Jia Kai-yu , Liao Yan-biao , Xia Fan , Zhao Zheng-gang , Chen Mao , Peng Yong 

TITLE=Transcatheter and Surgical Aortic Valve Replacement in Patients With Previous Cardiac Surgery: A Meta-Analysis

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=7

YEAR=2021

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2020.612155

DOI=10.3389/fcvm.2020.612155

ISSN=2297-055X

ABSTRACT=<p><bold>Background:</bold> Many patients who have aortic stenosis and are transcatheter aortic valve replacement (TAVR) candidates have underwent prior cardiac surgery (PCS). The aim of this study was to provide a robust summary comparison between patients with PCS who underwent TAVR vs. surgical aortic valve replacement (SAVR).</p><p><bold>Methods:</bold> We conducted a systematic review and meta-analysis of all published articles on PubMed/Medline, Ovid, EMBASE, and Scopus from 2002 to 2019.</p><p><bold>Results:</bold> A total of 13 studies were finally included, yielding a total of 23,148 participants. There was no statistical difference with 30-day [OR: 1.02 (0.86–1.21)] or 1-year mortality [OR: 1.18 (0.86–1.61)] between the two groups. Subgroup analysis revealed that high-risk patients who underwent TAVR with the transapical approach were associated with increased risk of mortality [OR: 1.45 (1.00–2.11)]. However, those who underwent TAVR with endovascular approach had a comparable outcome with SAVR.</p><p><bold>Conclusions:</bold> Primary outcomes after endovascular TAVR were similar to those with SAVR and superior to transapical TAVR treatment group in patients with PCS.</p>