AUTHOR=Rachwan Rayan Jo , Daher Ghassan E. , Fares Jawad , Rachoin Rachoin 

TITLE=Complete Resolution of a Large Bicuspid Aortic Valve Thrombus with Anticoagulation in Primary Antiphospholipid Syndrome

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=4

YEAR=2017

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2017.00059

DOI=10.3389/fcvm.2017.00059

ISSN=2297-055X

ABSTRACT=<p>Native aortic valve thrombosis in primary antiphospholipid syndrome (APLS) is a rare entity. We describe a 38-year-old man who presented with neurological symptoms and a cardiac murmur. Transthoracic echocardiography detected a large bicuspid aortic valve thrombus. Laboratory evaluation showed the presence of antiphospholipid antibodies. Anticoagulation was started, and serial echocardiographic studies showed complete resolution of the aortic valve vegetation after 4 months. The patient improved clinically and had no residual symptoms. This report and review of the literature suggests that vegetations in APLS can be treated successfully with conservative treatment, regardless of their size.</p>