Frontiers in Bioinformatics

Original Research

Accepted on 04 Apr 2025

Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection

Subhajit Ghosh
Sukhen Das Mandal
Subarna Thakur

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1522401

Original Research

Published on 04 Apr 2025

Harnessing computational immunology to design targeted subunit vaccines for infectious bursal disease in poultry

Elijah Kolawole Oladipo
Stephen Feranmi Adeyemo
Ayomiposi Isaiah Oshoneye
Hannah Blessing Akintola
Bolatito Islam Elegbede
Tobiloba Uren Ayoomoba
Dorcas Ayomide Atilade
Omolara Omoboye Adegboye
Abuoma Elizabeth Ejikeme
Chris Olamide Balogun

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1562997

286 views

Original Research

Accepted on 31 Mar 2025

Genomic analysis of Listeria monocytogenes strains from dairy products in Ethiopia

Mebrie Zemene Kinde
Bizuayehu Kerisew
Abebe Tesfaye Gessese
Tegegne Eshetu

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1572241

Original Research

Accepted on 31 Mar 2025

Using AlphaFold-Multimer to Study Novel Protein-Protein Interactions of Predation Essential Hypothetical Proteins in Bdellovibrio

Ibukun John Abulude
Isabel Cristina Rodríguez Luna
Alejandro Sánchez Varela
Andrew Camilli
Daniel E Kadouri
Xianwu Guo

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1566486

Original Research

Published on 28 Mar 2025

Identification of key hub genes in pancreatic ductal adenocarcinoma: an integrative bioinformatics study

Kankana Bhattacharjee
Avik Sengupta
Rahul Kumar
Aryya Ghosh

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1536783

398 views

Original Research

Accepted on 27 Mar 2025

Identification of novel drug targets and small molecule discovery for MRSA infections

Nandhakumar Subramani
Subhashree Venugopal

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1562596

Original Research

Accepted on 26 Mar 2025

Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotions using in silico techniques

Behnam Hasannejad-asl
Farkhondeh Pooresmaeil
Sareh Azadi
Ali Najafi
Ali Esmaeili
Saeid Bagheri-Mohammadi
Bahram Kazemi

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1570101

Original Research

Published on 26 Mar 2025

Inhibition potential of margolonone and isomargolonone against the dengue virus protease using molecular modeling approaches

Gourav Choudhir
Faiza Iram
Israil
Mohammad Shahid
Anas Shamsi
Md Imtaiyaz Hassan
Asimul Islam

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1517115

253 views

Original Research

Published on 26 Mar 2025

Comprehensive structural and functional analyses of RAD50 nsSNPs: from prediction to impact assessment

Samina Malik
Mirza Jawad Ul Hasnain
Gul Zaib
Haleema Saadia
Arif Malik
Ayesha Zahid

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1535482

228 views

Original Research

Published on 26 Mar 2025

Streptomyces sp. VITGV156 secondary metabolite binds pathogenic protein PBP2a and Beta-lactamase

Veilumuthu Pattapulavar
Sathiyabama Ramanujam
Manisha Shah
Muthu Kumar Thirunavukkarasu
Sivakumar Arumugam
Ramanathan Karuppasamy
Antony V. Samrot
K. Deepasree
Subhashree Venugopal
John Godwin Christopher

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1544800

496 views

Original Research

Published on 25 Mar 2025

Molecular dynamic simulations to assess the structural variability of ClpV from Enterobacter cloacae

Tehrim Motiwala
Babalwa Nyide
Thandeka Khoza

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1498916

225 views

Mini Review

Accepted on 24 Mar 2025

Mini-review: Primer on Machine Learning Applications in Brain Immunology

Niklas Binder
Ashkan Khavaran
Roman Sankowski

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1554010

Original Research

Accepted on 24 Mar 2025

Transcripts derived from AmnSINE1 repetitive sequences are depleted in the cortex of autism spectrum disorder patients

Nicolina Sciaraffa
Daniele Santoni
andrea li greci
swonild ilenia genovese
Claudia Coronnello
Walter Arancio

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1532981

Original Research

Published on 20 Mar 2025

Divergent evolution of low-complexity regions in the vertebrate CPEB protein family

Serena Vaglietti
Stefania Boggio Bozzo
Mirella Ghirardi
Ferdinando Fiumara

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1491735

439 views

Original Research

Accepted on 19 Mar 2025

Classification of Collagen Remodeling in Asthma using Second-Harmonic Generation Imaging, Supervised Machine Learning and Texture-based Analysis

Natasha Nikita Kunchur
Joshua James Andrew Poole
Jesse Levine
Rebecca Thornhill
Tillie-Louise Hackett
Leila Mostaço-Guidolin

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1539936

130 views

Brief Research Report

Published on 18 Mar 2025

ORF1ab codon frequency model predicts host-pathogen relationship in orthocoronavirinae

Phillip E. Davis
Joseph A. Russell

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1562668

347 views

432 Publications

Volume 5 - 2025

Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection

Harnessing computational immunology to design targeted subunit vaccines for infectious bursal disease in poultry

Genomic analysis of Listeria monocytogenes strains from dairy products in Ethiopia

Using AlphaFold-Multimer to Study Novel Protein-Protein Interactions of Predation Essential Hypothetical Proteins in Bdellovibrio

Identification of key hub genes in pancreatic ductal adenocarcinoma: an integrative bioinformatics study

Identification of novel drug targets and small molecule discovery for MRSA infections

Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotions using in silico techniques

Inhibition potential of margolonone and isomargolonone against the dengue virus protease using molecular modeling approaches

Comprehensive structural and functional analyses of RAD50 nsSNPs: from prediction to impact assessment

Streptomyces sp. VITGV156 secondary metabolite binds pathogenic protein PBP2a and Beta-lactamase

Molecular dynamic simulations to assess the structural variability of ClpV from Enterobacter cloacae

Mini-review: Primer on Machine Learning Applications in Brain Immunology

Transcripts derived from AmnSINE1 repetitive sequences are depleted in the cortex of autism spectrum disorder patients

Divergent evolution of low-complexity regions in the vertebrate CPEB protein family

Classification of Collagen Remodeling in Asthma using Second-Harmonic Generation Imaging, Supervised Machine Learning and Texture-based Analysis

ORF1ab codon frequency model predicts host-pathogen relationship in orthocoronavirinae