Frontiers in Bioinformatics

Original Research

Published on 19 Jun 2024

A comprehensive multi-omics analysis reveals unique signatures to predict Alzheimer’s disease

in Integrative Bioinformatics

Michael Vacher
Rodrigo Canovas
Simon M. Laws
James D. Doecke

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1390607

2,325 views
4 citations

Original Research

Published on 24 May 2024

Human cytokine and coronavirus nucleocapsid protein interactivity using large-scale virtual screens

in Protein Bioinformatics

Phillip J. Tomezsko
Colby T. Ford
Avery E. Meyer
Adam M. Michaleas
Rafael Jaimes

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1397968

2,120 views
7 citations

Original Research

Published on 24 May 2024

Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV

in Genomic Analysis

Joshua Zhang
Mary E. Sehl
Roger Shih
Elizabeth Crabb Breen
Fengxue Li
Ake T. Lu
Jay H. Bream
Priya Duggal
Jeremy Martinson
Steven M. Wolinsky

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1357889

2,214 views
1 citation

Original Research

Published on 24 May 2024

Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV

in Genomic Analysis

Mary E. Sehl
Elizabeth Crabb Breen
Roger Shih
Fengxue Li
Joshua Zhang
Peter Langfelder
Steve Horvath
Jay H. Bream
Priya Duggal
Jeremy Martinson

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1356509

2,160 views
1 citation

Original Research

Published on 14 May 2024

Pathway-based analyses of gene expression profiles at low doses of ionizing radiation

in Integrative Bioinformatics

Xihaier Luo
Seyednami Niyakan
Patrick Johnstone
Sean McCorkle
Gilchan Park
Vanessa López-Marrero
Shinjae Yoo
Edward R. Dougherty
Xiaoning Qian
Francis J. Alexander

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1280971

1,269 views
1 citation

Editorial

Published on 03 May 2024

Editorial: Computational methods for analysis of DNA methylation data, volume II

in Genomic Analysis

Pietro Di Lena
Christine Nardini
Matteo Pellegrini

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1415791

851 views

Original Research

Published on 16 Apr 2024

PAGER-scFGA: unveiling cell functions and molecular mechanisms in cell trajectories through single-cell functional genomics analysis

in Integrative Bioinformatics

Fengyuan Huang
Robert S. Welner
Jake Y. Chen
Zongliang Yue

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1336135

1,895 views

Review

Published on 11 Apr 2024

From complex data to clear insights: visualizing molecular dynamics trajectories

in Data Visualization

Hayet Belghit
Mariano Spivak
Manuel Dauchez
Marc Baaden
Jessica Jonquet-Prevoteau

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1356659

3,924 views
7 citations

Original Research

Published on 08 Apr 2024

Prediction of polyspecificity from antibody sequence data by machine learning

in Drug Discovery in Bioinformatics

Szabolcs Éliás
Clemens Wrzodek
Charlotte M. Deane
Alain C. Tissot
Stefan Klostermann
Francesca Ros

Frontiers in Bioinformatics

doi 10.3389/fbinf.2023.1286883

3,801 views
3 citations

Original Research

Published on 04 Apr 2024

BayesAge: A maximum likelihood algorithm to predict epigenetic age

in Genomic Analysis

Lajoyce Mboning
Liudmilla Rubbi
Michael Thompson
Louis-S. Bouchard
Matteo Pellegrini

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1329144

1,718 views
4 citations

Original Research

Published on 03 Apr 2024

bootGSEA: a bootstrap and rank aggregation pipeline for multi-study and multi-omics enrichment analyses

in Integrative Bioinformatics

Shamini Hemandhar Kumar
Ines Tapken
Daniela Kuhn
Peter Claus
Klaus Jung

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1380928

1,662 views
2 citations

Brief Research Report

Published on 27 Mar 2024

A systematic evaluation of state-of-the-art deconvolution methods in spatial transcriptomics: insights from cardiovascular disease and chronic kidney disease

in Integrative Bioinformatics

Alban Obel Slabowska
Charles Pyke
Henning Hvid
Leon Eyrich Jessen
Simon Baumgart
Vivek Das

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1352594

3,518 views
3 citations

Opinion

Published on 19 Mar 2024

Sequencing technologies and hardware-accelerated parallel computing transform computational genomics research

in Genomic Analysis

Michael Olbrich
Lennart Bartels
Inken Wohlers

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1384497

1,720 views

Original Research

Published on 15 Mar 2024

An interactive visualization tool for educational outreach in protein contact map overlap analysis

in Integrative Bioinformatics

Kevan Baker
Nathaniel Hughes
Sutanu Bhattacharya

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1358550

2,240 views
1 citation

Review

Published on 15 Mar 2024

Ten common issues with reference sequence databases and how to mitigate them

in Genomic Analysis

Samuel D. Chorlton

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1278228

4,930 views
11 citations

Technology and Code

Published on 12 Mar 2024

ursaPGx: a new R package to annotate pharmacogenetic star alleles using phased whole-genome sequencing data

in Evolutionary Bioinformatics

Gennaro Calendo
Dara Kusic
Jozef Madzo
Neda Gharani
Laura Scheinfeldt

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1351620

1,456 views
2 citations

Navigation group

Articles

A comprehensive multi-omics analysis reveals unique signatures to predict Alzheimer’s disease

Human cytokine and coronavirus nucleocapsid protein interactivity using large-scale virtual screens

Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV

Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV

Pathway-based analyses of gene expression profiles at low doses of ionizing radiation

Editorial: Computational methods for analysis of DNA methylation data, volume II

PAGER-scFGA: unveiling cell functions and molecular mechanisms in cell trajectories through single-cell functional genomics analysis

From complex data to clear insights: visualizing molecular dynamics trajectories

Prediction of polyspecificity from antibody sequence data by machine learning

BayesAge: A maximum likelihood algorithm to predict epigenetic age

bootGSEA: a bootstrap and rank aggregation pipeline for multi-study and multi-omics enrichment analyses

A systematic evaluation of state-of-the-art deconvolution methods in spatial transcriptomics: insights from cardiovascular disease and chronic kidney disease

Sequencing technologies and hardware-accelerated parallel computing transform computational genomics research

An interactive visualization tool for educational outreach in protein contact map overlap analysis

Ten common issues with reference sequence databases and how to mitigate them

ursaPGx: a new R package to annotate pharmacogenetic star alleles using phased whole-genome sequencing data