94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
REVIEW article
Front. Bioeng. Biotechnol.
Sec. Biomaterials
Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1553653
This article is part of the Research Topic Environmentally-Responsive Biomaterials for Major Diseases Treatment View all 8 articles
Recent Advances of Polydopamine-Coated Metal-Organic Frameworks for Cancer Therapy
Provisionally accepted- 1 Medical College, Yangzhou University, Yangzhou, China
- 2 Teaching Center of Pathogenic Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin, China
- 3 Jining Cancer Hospital, Jining, Shandong Province, China
- 4 Guangxi University of Science and Technology, Liuzhou, Guangxi Zhuang Region, China
- 5 The Affiliated Taizhou People's Hospital, Nanjing Medical University, Taizhou, China
The creation and development of classical multifunctional nanomaterials are crucial for the advancement of nanotherapeutic treatments for tumors. Currently, metal-organic frameworks (MOFs) modified with polydopamine (PDA) are at the hotspot of nanomedicine research, particularly in tumor diagnostics and therapy, owing to their exceptional biocompatibility, expansive specific surface area, multifaceted functionalities, and superior photothermal properties, which have yield significant anti-tumor research outcomes. Consequently, leveraging the exceptional capabilities of MOFs, a range of anti-cancer strategies has been devised, including intelligent drug delivery systems, photodynamic therapy, and photothermal therapy, which are particularly tailored for the tumor microenvironment. In order to further insight into the role of MOFs@PDA in cancer diagnosis and
Keywords: Metal organic frameworks (MOFs), polydopamine (PDA), MOFs@PDA, Cancer, Diagnosis and therapy
Received: 31 Dec 2024; Accepted: 04 Mar 2025.
Copyright: © 2025 He, Wang, Zhou, Li and Shang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jingchao He, Medical College, Yangzhou University, Yangzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.