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REVIEW article
Front. Bioeng. Biotechnol.
Sec. Biomaterials
Volume 13 - 2025 |
doi: 10.3389/fbioe.2025.1550089
This article is part of the Research Topic Advanced Functional Materials for Disease Diagnosis, Drug Delivery and Tissue Repair View all 14 articles
Recent research progress on metal ions and metal-based nanomaterials in tumor therapy
Provisionally accepted- 1 Shenyang Medical College, Shenyang, Liaoning Province, China
- 2 Ningde Normal University, Ningde, Fujian, China
- 3 College of Basic Medical Sciences, Shenyang Medical College, Shenyang, China
Tumors, as a disease that seriously threatens human health, have always been a major challenge in the field of medicine. Currently, the main methods of tumor treatment include surgery, radiotherapy, chemotherapy, etc., but these traditional treatment methods often have certain limitations. In addition, tumor recurrence and metastasis are also difficult problems faced in clinical treatment. In this context, the importance of metal-based nanomaterials in tumor therapy is increasingly highlighted. Metal-based nanomaterials possess unique physical, chemical, and biological properties, providing new ideas and methods for tumor treatment. Metal-based nanomaterials can achieve targeted therapy for tumors through various mechanisms, reducing damage to normal tissues; they can also serve as drug carriers, improving the stability and bioavailability of drugs; at the same time, some metal-based nanomaterials also have photothermal, photodynamic, and other characteristics, which can be used for phototherapy of tumors. This review examines the latest advances in the application of metal-based nanomaterials in tumor therapy within past 5 years, and presents prospective insights into the future applications
Keywords: Metal-based nanomaterials, tumor therapy, ferroptosis, calcium overload, cuproptosis, Immunotherapy
Received: 22 Dec 2024; Accepted: 20 Jan 2025.
Copyright: © 2025 Xu, Reheman and Feng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wenhua Feng, College of Basic Medical Sciences, Shenyang Medical College, Shenyang, China
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