Skip to main content

ORIGINAL RESEARCH article

Front. Bioeng. Biotechnol.

Sec. Biomechanics

Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1543792

This article is part of the Research Topic Biomechanics in Orthopaedic Diseases and Surgery, Volume II View all 12 articles

Surgical Factors That Contribute To Tibial Periprosthetic Fracture After Cementless Oxford Unicompartmental Knee Replacement: A Finite Element Analysis

Provisionally accepted
  • 1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom
  • 2 School of Engineering, Computing and Mathematics, Faculty of Technology, Design and Environment, Oxford Brookes University, Oxford, England, United Kingdom
  • 3 Department of Orthopaedic Surgery and Joint Surgery Centre, Takatsuki General Hospital, Takatsuki, Ōsaka, Japan

The final, formatted version of the article will be published soon.

    Background: Tibial periprosthetic fracture (TPF) is a severe complication of cementless Oxford Unicompartmental Knee Replacement (OUKR) with patient risk factors including small tibial size and tibia vara with an overhanging medial tibial condyle. Surgical factors also influence fracture but remain poorly defined. This finite element (FE) analysis study identified surgical risk factors for TPF after OUKR and determined the optimal tibial component positioning to minimise fracture risk.Methods: Knees in two very high-risk, small, bilateral OUKR patients who had a TPF in one knee and a good result in the other were studied with FE analysis. Each patient's unfractured tibia was used as a comparator to study surgical factors. The tibial geometries were segmented from the preoperative CT scans and FE models were built with the tibial components implanted in their postoperative positions. The resections in the fractured and unfractured tibias were compared regarding their mediolateral position, distal-proximal position, internal-external rotation and varus-valgus orientation. Models of the TPF tibial resections in the contralateral sides were also built in both patients. The risk of TPF was assessed by examining the magnitude and location of the highest maximum principal stress.In both patients, large differences were found in the position and orientation of the tibial components in the fractured and unfractured tibias with the components in the fractured tibias placed more medially and distally. Suboptimal saw cuts resulted in poor positioning of the tibial components and created very high local stresses in the bone, particularly anteriorly (157 MPa and 702 MPa in the fractured side vs 49 MPa and 63 MPa in the unfractured side in patient 1 and 2 respectively), causing fractures.In small patients with marked tibia vara the surgery is unforgiving. To avoid fracture, the horizontal cut should be conservative, aiming for a 3 bearing, the vertical cut should abut the apex of the medial tibial spine, and extreme internal or external rotation should be avoided. The component should be aligned with the posterior cortex and should not overhang anteriorly. In addition, contrary to current recommendations, the tibial component should be placed in varus (about 5°).

    Keywords: Oxford unicompartmental knee, Finite Element Analysis, periprosthetic tibial fracture, Cementless fixation, Fracture risk, surgical techniques

    Received: 11 Dec 2024; Accepted: 24 Mar 2025.

    Copyright: © 2025 Min, Marks, Mellon, Takafumi and Murray. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xiaoyi Min, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    94% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more