AUTHOR=Besleaga Mihail , Ebner Katharina , Glieder Anton , Spadiut Oliver , Kopp Julian TITLE=Chances and drawbacks of derepressed recombinant enzyme production in continuous cultivations with Komagataella phaffii JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=13 YEAR=2025 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2025.1523037 DOI=10.3389/fbioe.2025.1523037 ISSN=2296-4185