Rui Lv Daochun Li Shiwei Zhao ^* Peng Shu Jinwu Xiang

• Beihang University, Beijing, China

A coupled balloon-stent-plaque-artery model and a fluid domain model, reflecting structural deformation, are developed to explore the interaction between coronary stents and stenotic vessels, and their impact on hemodynamics. The study investigates the influence of stent connectors on the mechanical response of both the plaque and artery, with hemodynamic analyses performed across varying exercise intensities. The results demonstrate that the model effectively simulates the gradual expansion of the stent, plaque, and artery, as well as the recoil behavior post-expansion. The gradual adaptation of the stent to the plaque during the initial expansion phase helps mitigate the adverse effects of the dog-boning phenomenon. Areas of low time-averaged wall shear stress (TAWSS) and high relative residence time (RRT) are observed at both ends and near the stent, with a general decreasing trend as exercise intensity increases. Additionally, the study quantifies the changes in hemodynamic characteristics across different physiological states. Specifically, the low TAWSS and high RRT areas are significantly reduced during moderate exertion, with no further substantial reduction observed at maximum exertion. These findings provide valuable insights for the design of stent connectors and offer guidance on optimal exercise intensity for patients undergoing stent interventions.