AUTHOR=Sun Qi , Nan Xin-Yu , Wang Hui , Pan Shuo , Ji Gang , Guo Ya-Feng , Zhao Ya-Heng , Li Gao-Cen , Guo Shao-Shi , Lin Lu-Feng , Jin Yu-Jie , Zhang Xue Li , Liu Chang-Cheng , Liu Guo-Bin TITLE=Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=12 YEAR=2025 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1514483 DOI=10.3389/fbioe.2024.1514483 ISSN=2296-4185