Skip to main content

MINI REVIEW article

Front. Bioeng. Biotechnol.
Sec. Biomaterials
Volume 12 - 2024 | doi: 10.3389/fbioe.2024.1456694
This article is part of the Research Topic Pharmaceutical Biomaterials View all 18 articles

Research Progress on Blood Compatibility of Hemoperfusion Adsorbent Materials

Provisionally accepted
Liangqing Zhang Liangqing Zhang 1Guohao Liu Guohao Liu 2Qingping Xia Qingping Xia 3Li Deng Li Deng 3*
  • 1 Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
  • 2 Affiliated Hospital of Jilin Medical University, Jilin, China
  • 3 The People’s Hospital of Gaozhou, Gaozhou, China

The final, formatted version of the article will be published soon.

    This comprehensive review examines the latest developments in improving the blood compatibility of hemoperfusion adsorbents. By leveraging advanced coating and modification techniques, including albumin-collodion, cellulose, hydrogel, and heparin coatings, notable enhancements in blood compatibility have been achieved across diverse adsorbent types, such as carbon-based, resin-based, and polysaccharide-based materials. Despite promising laboratory results, the intricate manufacturing processes and elevated costs present significant challenges for broad clinical application. Therefore, future endeavors should focus on cost-benefit analysis, large-scale production strategies, in-depth exploration of blood-material interactions, and innovative technologies to propel the development of safer and more effective blood purification therapies.

    Keywords: Hemoperfusion, Adsorbent materials, blood compatibility,, Research progress, Biocompatibility

    Received: 29 Jun 2024; Accepted: 19 Sep 2024.

    Copyright: © 2024 Zhang, Liu, Xia and Deng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Li Deng, The People’s Hospital of Gaozhou, Gaozhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.