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REVIEW article

Front. Bioeng. Biotechnol.
Sec. Biofabrication
Volume 12 - 2024 | doi: 10.3389/fbioe.2024.1439499
This article is part of the Research Topic State-of-art of 3D Printing and Bioprinting Technology in various domains of Biomedicine, Tissue Engineering and Regenerative Medicine View all 10 articles

3D printing patch as a wound healing platform of tympanic membrane perforation

Provisionally accepted
灏 薛 灏 薛 1Chen Sheng Jia Chen Sheng Jia 1*Hu Yi Hu Yi 2*Shen Yi Shen Yi 3*
  • 1 Ningbo University, Ningbo, China
  • 2 Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang Province, China
  • 3 Ningbo Second Hospital, Ningbo, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    Tympanic membrane perforation (TMP) is one of the most common conditions in otolaryngology worldwide, and hearing damage caused by inadequate or prolonged healing can be distressing for patients. This article examines the rationale for utilizing three-dimensional (3D) printing to produce scaffolds for repairing, compares the advantages and disadvantages of 3D printed and bioprinted grafts with traditional autologous materials and other tissue engineering materials in TMP repair, and highlights the practical and clinical significance of 3D printing in TMP repair while discussing the current progress and promising future of 3D printing and bioprinting. There is a limited number of reviews specifically dedicated to 3D printing for TMP repair. The majority reviews offer a general overview of the applications of 3D printing in the broader realm of tissue regeneration, with some mention of TMP repair. Alternatively, they explore the biopolymers, cells, and drug molecules utilized for TMP repair. However, more indepth analysis is needed on the strategies for selecting bio-inks that integrate biopolymers, cells, and drug molecules for tympanic membrane repair.

    Keywords: Tympanic Membrane Perforation, 3D printing, Tissue Engineering, Regeneration, Wound Healing

    Received: 28 May 2024; Accepted: 19 Jul 2024.

    Copyright: © 2024 薛, Sheng Jia, Yi and Yi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Chen Sheng Jia, Ningbo University, Ningbo, China
    Hu Yi, Ningbo Medical Centre Lihuili Hospital, Ningbo, 315010, Zhejiang Province, China
    Shen Yi, Ningbo Second Hospital, Ningbo, 315010, Zhejiang Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.