AUTHOR=Dindorf Carlo , Dully Jonas , Konradi Jürgen , Wolf Claudia , Becker Stephan , Simon Steven , Huthwelker Janine , Werthmann Frederike , Kniepert Johanna , Drees Philipp , Betz Ulrich , Fröhlich Michael 

TITLE=Enhancing biomechanical machine learning with limited data: generating realistic synthetic posture data using generative artificial intelligence

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=12

YEAR=2024

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1350135

DOI=10.3389/fbioe.2024.1350135

ISSN=2296-4185

ABSTRACT=<p><bold>Objective:</bold> Biomechanical Machine Learning (ML) models, particularly deep-learning models, demonstrate the best performance when trained using extensive datasets. However, biomechanical data are frequently limited due to diverse challenges. Effective methods for augmenting data in developing ML models, specifically in the human posture domain, are scarce. Therefore, this study explored the feasibility of leveraging generative artificial intelligence (AI) to produce realistic synthetic posture data by utilizing three-dimensional posture data.</p><p><bold>Methods:</bold> Data were collected from 338 subjects through surface topography. A Variational Autoencoder (VAE) architecture was employed to generate and evaluate synthetic posture data, examining its distinguishability from real data by domain experts, ML classifiers, and Statistical Parametric Mapping (SPM). The benefits of incorporating augmented posture data into the learning process were exemplified by a deep autoencoder (AE) for automated feature representation.</p><p><bold>Results:</bold> Our findings highlight the challenge of differentiating synthetic data from real data for both experts and ML classifiers, underscoring the quality of synthetic data. This observation was also confirmed by SPM. By integrating synthetic data into AE training, the reconstruction error can be reduced compared to using only real data samples. Moreover, this study demonstrates the potential for reduced latent dimensions, while maintaining a reconstruction accuracy comparable to AEs trained exclusively on real data samples.</p><p><bold>Conclusion:</bold> This study emphasizes the prospects of harnessing generative AI to enhance ML tasks in the biomechanics domain.</p>