AUTHOR=Zhang Shuquan , Tang Chaokun , Feng Jiangtao , Wang Qi , Li Chenguang , Zhang Weihao , Zhou Fengxin , Xue Feng , Xu Baoshan , Lyu Shaoyuan , Chen Minfang , Wang Hao 

TITLE=The in vivo and in vitro corrosion behavior of MgO/Mg-Zn-Ca composite with different Zn/Ca ratio

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2023.1222722

DOI=10.3389/fbioe.2023.1222722

ISSN=2296-4185

ABSTRACT=<p>The effect of Zn/Ca ratio on the corrosion behavior of Mg–3Zn-0.2Ca-1.0MgO (3ZX) and Mg–1Zn-0.2Ca-1.0MgO (ZX) was investigated on the as-extruded specimens. Microstructure observations revealed that the low Zn/Ca ratio led to the grain growth from 1.6 µm in 3ZX to 8.1 µm in ZX. At the same time, the low Zn/Ca ratio changed the nature of second phase from the existence of Mg-Zn and Ca<sub>2</sub>Mg<sub>6</sub>Zn<sub>3</sub> phases in 3ZX to the dominated Ca<sub>2</sub>Mg<sub>6</sub>Zn<sub>3</sub> phase in ZX. The local galvanic corrosion caused by the excessive potential difference was alleviated obviously due to the missing of MgZn phase in ZX. Besides, the <italic>in vivo</italic> experiment also showed that ZX composite exhibited a good corrosion performance and the bone tissue around the implant grew well.</p>