AUTHOR=Bao Siqi , Sun Shuanghui , Li Lin , Xu Lei 

TITLE=Synthesis and antibacterial activities of Ag-TiO2/ZIF-8

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2023.1221458

DOI=10.3389/fbioe.2023.1221458

ISSN=2296-4185

ABSTRACT=<p>In recent years, massive bacterial infections have led to human illness and death, reminding us of the urgent need to develop effective and long-lasting antimicrobial materials. In this paper, Ag-TiO<sub>2</sub>/ZIF-8 with good environmental friendliness and biological antibacterial activity was prepared by solvothermal method. The structure and morphology of the synthesized materials were characterized by XRD, FT-IR, SEM-EDS, TEM, XPS, and BET. To investigate the antibacterial activity of the synthesized samples, <italic>Escherichia coli</italic> and <italic>Bacillus subtilis</italic> were used as target bacteria for experimental studies of zone of inhibition, bacterial growth curves, minimum bactericidal concentration and antibacterial durability. The results demonstrated that 20 wt.%Ag-TiO<sub>2</sub>/ZIF-8 had the best bacteriostatic effect on <italic>E. coli</italic> and <italic>B. subtilis</italic> under dark and UV conditions compared to TiO<sub>2</sub> and ZIF-8. Under the same conditions, the diameter of the inhibition circle of 20 wt% Ag-TiO<sub>2</sub>/ZIF-8 is 8.5–11.5 mm larger than that of its constituent material 4 wt% Ag-TiO<sub>2</sub>, with more obvious antibacterial effect and better antibacterial performance. It is also proposed that the excellent antibacterial activity of Ag-TiO<sub>2</sub>/ZIF-8 is due to the synergistic effect of Ag-TiO<sub>2</sub> and ZIF-8 under UV light. In addition, the prepared material has good stability and durability with effective antimicrobial activity for more than 5 months.</p>