AUTHOR=Xu Wei , Wang Tao , Wang Yahui , Wu Xiaodi , Chen Yujie , Song Daiying , Ci Zheng , Cao Yilin , Hua Yujie , Zhou Guangdong , Liu Yu TITLE=An Injectable Platform of Engineered Cartilage Gel and Gelatin Methacrylate to Promote Cartilage Regeneration JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2022.884036 DOI=10.3389/fbioe.2022.884036 ISSN=2296-4185 ABSTRACT=
Cell–hydrogel constructs are frequently used as injectable platforms for irregular cartilage regeneration. However, cell–hydrogel constructs have obvious disadvantages, such as long culture times, high probability of infection, and poor cartilage formation capacity, significantly limiting their clinical translation. In this study, we aimed to develop a novel injectable platform comprising engineered cartilage gel (ECG) and gelatin methacrylate (GelMA) to improve cartilage regeneration. We first prepared an ECG by cutting the